Release Date: Friday, July 14, 2017    

Expiration Date: Saturday, July 14, 2018

Educational Overview
Serious bacterial infections place a substantial clinical and economic burden and are a leading cause of morbidity and mortality associated with hospital-acquired conditions. The CDC has identified a number of bacteria as urgent or serious threats, including ESBL-producing and carbapenem-resistant Enterobacteriaceae, multidrug-resistant P. aeruginosa, and C. difficile. In response to the rising threat and burden associated with these infections, antimicrobial stewardship programs are now mandatory in hospital settings to fulfill quality improvement criteria. This program is designed to build competence, confidence, and skills in the management of MDR Gram-negative infections and C. difficile infection. Expert faculty will review the latest approaches to treat these infections (e.g., optimized dosing, newer antimicrobials and alternative therapeutics) while also demonstrating how to incorporate antimicrobial stewardship strategies related to these infections.

Target Audience
This continuing medical education activity is planned to meet the needs of pharmacists and physicians in a variety of practice settings, including large and small healthcare systems, outpatient clinics, managed care organizations, long-term care facilities, and academia. This program targets clinicians who are responsible for caring for patients with serious bacterial infections.

Learning Objectives
Upon completing this activity, participants will be able to:

  • Explain current trends in antimicrobial resistance and identify patient risk factors for infection
  • Assess the role of newer antimicrobial agents as part of the armamentarium in the management of infections caused by multidrug-resistant Gram-negative bacteria and C. difficile
  • Evaluate the utility of novel approaches that reduce the risk of recurrent C. difficile infection in high-risk patients
  • Describe antimicrobial stewardship strategies that aim to minimize the burden of serious bacterial infections in healthcare institutions

Educational Format

This Online Presentation is based on the Satellite Symposium presented at MAD-ID Annual Meeting in Orlando, FL on
May 11, 2017. It is divided into 4 easy and quick to view episodes.


Understanding C. difficile and Gram-Negative Infections:
Are We There Yet?

Erik Dubberke, MD


Current Therapeutic Options for Antimicrobial-Resistant Gram-Negative Infections  

Kerry LaPlante, PharmD    


Applying the Latest Approaches in the Management of
C. difficile Infection and Recurrence


Learning by Sharing: Q and A       

Note: If you have received credit for attending the live program by the same name, you are not eligible to apply for credit for this online version.



Erik R. Dubberke, MD, MSPH, FSHEA

Associate Professor of Medicine
Director, Section of Transplant Infectious Diseases
Washington University School of Medicine
St. Louis, MO

Kerry L. LaPlante, PharmD, FCCP

Professor of Pharmacy
University of Rhode Island, College of Pharmacy
Adjunct Professor of Medicine
The Warren Alpert Medical School of Brown University
Senior Director of the Rhode Island Infectious Diseases Research (RIID) Program
Co-Director of Antimicrobial Stewardship Program and Infectious Diseases
Pharmacotherapy Specialist
Providence Veterans Medical Center
Providence, RI





AccreditationCenter for Independent Healthcare Education is accredited by the Accreditation Council for Pharmacy Education as a provider for continuing pharmacy education. Center has assigned 1.5 contact hours (0.15 CEUs) of continuing pharmacy education credits for participating in this activity.
 ACPE UAN: 0473-9999-17-008-H01-P
Activity type: Knowledge-based



This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Center for Independent Healthcare Education and Vemco MedEd, LLC. Center for Independent Healthcare Education (Center) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Center for Independent Healthcare Education designates this Enduring material for a maximum of 1.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For questions regarding the accreditation of this activity, please contact us at


Method of Participation and Instruction for Credit

  1. Review the entire CE information including target audience, learning objectives, and disclosures.
  2. Review each episode.
  3. Complete the Post Test, Evaluation, and Credit Application Form.
  4. Please note that to receive credit you must achieve a score of at least 70%
  5. Pharmacists: The information that you participated will be uploaded to CPEMonitor and you will be able to access your credits from the profile you set up with NABP. For more information, please visit
  6. Physicians: Certificate of Credit will be emailed within 4 weeks of successful completion of the activity.


Disclosure of Conflicts of Interest
In accordance with policies set forth by the Accreditation Council for Continuing Medical Education (ACCME), Center for Independent Healthcare Education requires all faculty members and spouses/significant others with an opportunity to affect the content of a continuing education activity to disclose any relevant financial relationships during the past 12 months with commercial interests. A commercial interest is any entity producing, marketing, reselling or distributing health care goods or services consumed by or used on patients. Relationships with commercial interests and conflicts of interest resulting from those relationships must be revealed to the audience and resolved prior to the activity.

Relevant relationships include roles such as speaker, author, consultant, independent contractor (including research), employee, investor, advisory committee member, board member, review panelist, and investigator. If a potential speaker or author indicates a possible conflict of interest, the conflict will be resolved by choosing another speaker or author for that topical area, or the slides, handouts, and/or monograph will be reviewed and approved by a qualified commercially-disinterested peer.

Erik R. Dubberke, MD has relevant financial relationships with the following commercial interests:
            Advisory Board: Synthetic biologics
            Consultant: Pfizer Inc., Valneva, Sanofi Pasteur, Merck & Co., Inc.
            Research Support: Sanofi Pasteur
Dr. Dubberke intends to discuss off-label uses of the following: Only oral vancomycin, fidaxomicin, and bezlotoxumab have FDA approved indications pertaining to CDI. All other treatments that will be discussed do not have approved indication.



Kerry L. LaPlante, PharmD has relevant financial relationships with the following commercial interests:
            Advisory Board: Cempra
            Research Support: Merck & Co., Inc., Pfizer Inc., The Medicines Company,
            Ocean Spray Cranberries, Inc.
Dr. LaPlante does not intend to discuss off-label uses of any products.

No other speakers, authors, planners or content reviewers have any relevant financial relationships to disclose.

Content review confirmed that the content was developed in a fair, balanced manner free from commercial bias. Disclosure of a relationship is not intended to suggest or condone commercial bias in any presentation, but it is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

There is no fee to participate in this activity.

Hardware/Software Requirements
Microsoft Internet Explorer, Mozilla Firefox, Apple Safari or Google Chrome with the QuickTime Plug-in
Note: Please disable any “pop-up blocker” features.

Adobe® Reader version 7 or above to view PDF files (If you do not have Adobe® Reader, you can download it for free from
Adobe Flash Player version 10 or above to view multimedia content (If you do
not have Adobe Flash Player, you can download it for free from

Connection Speed
Cable, DSL, or better of at least 300 kbps

System Check
Please e-mail any questions or concerns to

Copyright Statement
Copyright © 2017 Vemco MedEd, LLC. All Rights Reserved. Permission for accreditation use granted to Center for Independent Healthcare Education.

Privacy Policy

Joint Providership
This activity is jointly provided by Center for Independent Healthcare Education and Vemco MedEd.

Commercial Support

This activity is supported by an educational grant from Merck & Co., Inc.


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